Zopiclone, sold under the brand name Imovane among others, is a nonbenzodiazepine used to treat difficulty sleeping. Zopiclone is molecularly distinct from benzodiazepine drugs and is classed as a cyclopyrrolone. However, zopiclone increases the normal transmission of the neurotransmitter gamma-aminobutyric acid (GABA) in the central nervous system, via modulating benzodiazepine receptors in the same way that benzodiazepine drugs do.
Zopiclone is a sedative. It works by causing a depression or tranquilization of the central nervous system. After prolonged use, the body can become accustomed to the effects of zopiclone. When the dose is then reduced or the drug is abruptly stopped, withdrawal symptoms may result. These can include a range of symptoms similar to those of benzodiazepine withdrawal. Although withdrawal symptoms from therapeutic doses of zopiclone and its isomers (i.e., eszopiclone) do not typically present with convulsions and are therefore not considered life-threatening, patients may experience such significant agitation or anxiety that they seek emergency medical attention.
Zopiclone is used for the short-term treatment of insomnia where sleep initiation or sleep maintenance are prominent symptoms. Long-term use is not recommended, as tolerance, dependence, and addiction can occur. One low-quality study found that zopiclone is ineffective in improving sleep quality or increasing sleep time in shift workers – more research in this area has been recommended
Dosage and Usage Recommendations
It is always advisable to research the fact on anything you want to consume, especially medication. The correct dosage and usage instructions for medications such as sedatives should always be followed as rigorously as possible. Lower dosage zopiclone tablets are normally prescribed for elderly people exceeding the age of 65, and for people suffering from kidney or liver issues. However, standard dosage zopiclone 7.5mg tablets are the most commonly used to help induce sleep for insomnia sufferers. It is wise to take this medicine 30 – 60 minutes before sleep is desired, and preferably once you are in your bed. Do not make up for a missed dose of this medication by taking a double dosage the following night.
Daytime sleepiness, lightheadedness, bitter taste, dry mouth, headache, or an upset stomach may occur the first few days your body adjusts to the medicine. If any of these effects persist or become bothersome, tell your doctor. Tell your doctor if you develop: fast / pounding / irregular heartbeat, rash, changes in vision, slurred speech, severe drowsiness, memory loss, incoordination, confusion, depression, irritability, or other changes in behavior. drug. If you notice other effects not mentioned above, contact your doctor or pharmacist.
Zopiclone causes impaired driving skills similar to those of benzodiazepines. Long-term users of hypnotic drugs for sleep disorders develop only partial tolerance to adverse effects on driving with users of hypnotic drugs even after 1 year of use still showing an increased motor vehicle accident rate. Patients who drive motor vehicles should not take zopiclone unless they stop driving due to a significant increased risk of accidents in zopiclone users. Zopiclone induces impairment of psychomotor function. Driving or operating machinery should be avoided after taking zopiclone as effects can carry over to the next day, including impaired hand eye coordination.