Insulin lispro is a recombinant DNA sourced human insulin analogue. Humalog consists of zinc-insulin lispro crystals dissolved in a clear fluid. Humalog is used to control high blood sugar (glucose) in people with diabetes.
Humalog takes effect more rapidly and has a shorter duration of activity as compared to regular insulin.The rapid onset of activity requires Humalog to be given within 15 minutes before a meal. When necessary, Humalog may be given shortly after a meal instead (within 20 minutes of the start of the meal).
The time course of action of any insulin may vary to some extent in different individuals or at different times in the same individual. As with all insulin preparations,
the duration of action of Humalog is dependent on dose, site of injection, blood supply, temperature, and physical activity.
Proper control is important. Uncontrolled diabetes (hyperglycemia) over a long period of time can result in a number of serious problems such as blindness, kidney failure,
poor circulation/heart attacks, strokes and/or nerve damage.
These problems can be prevented or reduced by good diabetes management. This will require close and constant cooperation with your diabetes healthcare team including: yourself, your doctor and your diabetes educators (nurses, dietitians, social
workers, pharmacists and other healthcare professionals). Thus,you can lead an active, healthy and productive life by eating a balanced daily diet, exercising regularly, and taking your insulin injections as prescribed.
You have been instructed to test your blood and/or your urine regularly for glucose. If your blood tests consistently show above- or below-normal glucose levels or your urine tests consistently show the presence of glucose, your diabetes is
not properly controlled and you must let your doctor know
What the medication is used for:
Insulin is a hormone produced by the pancreas, a large gland that lies near the stomach. This hormone is necessary for the body’s correct use of food, especially sugar. Diabetes occurs when the pancreas does not make enough insulin to meet your body’s needs.To control your diabetes, your doctor has prescribed injections of insulin to keep your blood glucose at a near-normal level.
Dosage of Humalog
Diabetes mellitus type 1
The usual daily maintenance range is 0.5 to 1 unit / kg / day in divided doses; non-obese may require 0.4-0.6 unit / kg / day; Obesity may require 0.8-1.2 units / kg / day
Intermediate or long-acting insulin: About a third of daily insulin requirements
A fast-acting or short-acting pre-regulating insulin must be used to meet the rest of the daily insulin requirement.
Diabetes mellitus type 2
Intermediate or long-acting insulin: 10 units / day SC (or 0.1-0.2 units / kg / day) at bedtime usually recommended
Short-acting insulin: If necessary, start up to 4 units, 0.1 units / kg within 15 minutes before each meal or 10% of the basal dose; if A1C <8%, consider lowering the basal insulin dose by the same amount
Increase from 1 to 2 units or 10 to 15% of the week or week after self-monitoring of blood glucose.
Common Side Effects
Irritation at the injection site
Inflammation of the nose
Irritation of the throat
Warnings and precautions
Humalog should not be used if your blood glucose is too low or if you have low blood sugar. After treating your low blood sugar, follow your doctor’s instructions for how to use it. Your blood sugar level may be influenced by stress, illness, medical procedures, exercise, alcohol consumption or missing meals. Always ask your doctor before changing your schedule or insulin dose.
Humalog should not be used if you have allergies to anything in Humalog products.
Never share your injection pen, cartridge or syringe with anyone else even if you have changed the needle.