What Genotropin 12 mg is and what it is used for
Genotropin 12 mg is a recombinant human growth hormone (also called somatropin). It has the same structure as natural human growth hormone which is needed for bones and muscles to grow. It also helps your fat and muscle tissues to develop in the right amounts. It is recombinant meaning it is not made from human or animal tissue. In children, Genotropin is used to treat the following growth disturbances:
- If you are not growing properly and you do not have enough of your own growth hormone. · If you have Turner syndrome. Turner syndrome is a chromosomal error in girls that can affect growth – your doctor will have told you if you have this.
- If you have chronic renal (kidney) insufficiency. As kidneys lose their ability to function normally, this can affect growth.
- If you have Prader-Willi syndrome (a chromosomal disorder). Growth hormone will help you grow taller if you are still growing, and will also improve your body composition. Your excessive fat will decrease and your reduced muscle mass will improve.
- If you were small or too light at birth. Growth hormone can help you grow taller if you have not been able to catch up or maintain normal growth by four years of age or later.
Genotropin is used to treat persons with pronounced growth hormone deficiency. This can start during adult life, or it can continue from childhood. If you have been treated with Genotropin 12 mg for growth hormone deficiency during childhood, your growth hormone status will be retested after completion of growth. If severe growth hormone deficiency is confirmed, your doctor will propose continuation of Genotropin treatment. You should only be given this medicine by a doctor who has experience with growth hormone treatment and who has confirmed your diagnosis.
In bodybuilders, athletes Genotropin 12 mg are known to improve their physical performance, their muscle mass, burn fat and their immune system.
You should only be given this medicine by a doctor who has experience with growth hormone treatment and who has confirmed your diagnosis.
Before You UseGenotropin 12 mg
Do not use Genotropin and tell your doctor if
- You are allergic (hypersensitive) to somatropin or any of the other ingredients of Genotropin.
- You have an active tumour (cancer). Tumours must be inactive and you must have finished your anti-tumour treatment before you start your treatment with Genotropin.
- You are seriously ill (for example, complications following open heart surgery, abdominal surgery, acute respiratory failure, accidental trauma or similar conditions). If you are about to have, or have had, a major operation, or go into hospital for any reason, tell your doctor and remind the other doctors you are seeing that you use growth hormone.
- Genotropin has been prescribed to stimulate growth but you have already stopped growing (closed epiphyses)
How To Use Genotropin 12 mg
Recommended dosage The dose depends on your size, the condition for which you are being treated and how well growth hormone works for you. Everyone is different. Your doctor will advise you about your individualised dose of Genotropin in milligrams (mg) from either your body weight in kilograms (kg) or your body surface area calculated from your height and weight in square metres (m2 ), as well as your treatment schedule. Do not change the dosage and treatment schedule without consulting your doctor.
Children with growth hormone deficiency: From 0.16 to 0.24 mg / kg body weight per week. Higher doses can be used. When growth hormone deficiency continues in adolescence, treatment with GENOTROPIN should be continued until the end of your physical development.
Young girls with Turner syndrome: 0.33 mg / kg body weight per week.
Children with a small idiopathic size: up to 0.47 mg / kg body weight per week.
Children born with a smaller height or weight than expected and having a growth disorder: up to 0.48 mg / kg body weight per week. Your doctor will decide on the most appropriate dose and duration of treatment. Treatment should be discontinued: i) after the first year if you do not respond to treatment or ii) if you have reached your final size and have stopped growing.
Adults with growth hormone deficiency: You should start with a dose of 0.15 to 0.3 mg per day. This dosage will be gradually increased or decreased depending on blood test results as well as clinical response and side effects.
Bodybuilders, athletes for fat loss, 2 to 4 IU can be taken daily. And in order to gain muscle mass, the dosage is between 6 IU and 8 IU taken at one time or divided into two doses 6 days a week, in the morning and evening, with a stop on the 7th day. Of course, the cycle should last between 4 and 6 months to give significant results in muscle.
What Genotropin 12 mg contains
The Genotropin contains
- The active substance is somatropin
- One cartridge contains 5.3 mg or 12 mg of somatropin
- After reconstitution the concentration of somatropin is 5.3 mg or 12 mg per ml.
- The other ingredients in the powder are: glycine (E640), mannitol (E421), sodium dihydrogen phosphate anhydrous (E339), and disodium phosphate anhydrous (E339).
- The ingredients in the solvent are: water for injections, mannitol (E421) and metacresol.
Possible Side Effects of Genotropin 12 mg
Like all medicines, Genotropin can cause side effects, although not everybody gets them. The very common and common side effects in adults may start within the first months of treatment and may either stop spontaneously or if your dose is reduced.
Very common side effects (likely to occur in more than 1 in 10 patients) include:
- Joint pain
- Water retention (which shows as puffy fingers or swollen ankles).
Common side effects (likely to occur in fewer than 1 in 10 patients) include:
- Temporary reddening, itchiness or pain at the injection site.
- Joint pain
- Numbness / tingling,
- Stiffness in the arms and legs, muscle pain,
- Pain or burning sensation in the hands or underarms (known as Carpal Tunnel Syndrome).
Uncommon side effects (likely to occur in fewer than 1 in 100 patients) include:
- Water retention (which shows as puffy fingers or swollen ankles, for a short time at the start of treatment).
Rare side effects (likely to occur in fewer than 1 in 1,000 patients) include:
- Numbness / tingling
- Leukaemia (This has been reported in a small number of growth hormone deficiency patients, some of whom have been treated with somatropin. However, there is no evidence that leukaemia incidence is increased in growth hormone recipients without predisposing factors).
- Increased intracranial pressure (which causes symptoms such as strong headache, visual disturbances or vomiting).
- Muscle pain.